Abstract: Cigarette smoking is considered as addictive and destructive behaviour. It creates health problems and variation in different parameters of blood. Cigarette smoking also causes environmental pollution by releasing toxic air pollutants into the atmosphere. Analysis of Lead (Pb), Cadmium (Cd) and Iron (Fe) in blood of smokers and non-smokers was done by Atomic Absorption Spectroscopy and there was also comparison of effect of cigarette smoking on haemoglobin (Hb) between smokers and non-smokers before and after medication. Samples of smokers and non-smokers were collected from different areas of Lahore. After experimentation, statistics applied for the conclusion. Samples of smokers and non-smokers were collected to compare the effect of smoking on Hb before and after medication. Smokers and non-smokers were medicated by medicine Surbex Z for one week. The Hb level of smokers and nonsmokers was noted before and after medication. Time duration has been taken into account for effective medication.